Aripiprazole: Uses, Side Effects and Monitoring
A patient guide to Aripiprazole — an atypical antipsychotic used for schizophrenia, bipolar disorder, and as an adjunct for depression — uses, side effects, monitoring, and precautions.
Aripiprazole is an atypical antipsychotic with a distinct mechanism of action compared to many other antipsychotics, generally associated with a more favourable metabolic side-effect profile.
Uses
- Schizophrenia
- Bipolar disorder
- As an adjunct treatment for depression not fully responding to an antidepressant alone
Common Side Effects
- Akathisia — an inner restlessness or urge to move, more characteristic of this medication than sedation
- Nausea, particularly early in treatment
- Headache
- Insomnia in some patients
Monitoring
Routine metabolic monitoring (weight, blood glucose, lipids) is still recommended, though aripiprazole is generally considered more metabolically neutral than some other antipsychotics.
Precautions
- Antipsychotic medications, including aripiprazole, carry a specific caution regarding increased mortality risk when used for dementia-related behavioural symptoms in elderly patients
- Akathisia should be reported to your psychiatrist, as it can be uncomfortable and may require dose adjustment
- Disclose all other medications to check for potential interactions
Frequently Asked Questions
Frequently Asked Questions
What is akathisia?
Akathisia is a feeling of inner restlessness or a strong urge to move, which is a recognised side effect of aripiprazole and some other antipsychotics; report this to your psychiatrist if it occurs, as adjustments can help.
Does Aripiprazole cause significant weight gain?
It is generally considered more weight-neutral than many other antipsychotics, though individual response varies and monitoring is still recommended.
Important Note
This page provides general educational information about Aripiprazole and does not replace individual medical advice. Always take this medication as prescribed by your psychiatrist, and report any concerning symptoms promptly.
Reviewed by Dr. Muhammad Shoaib Zafar, Consultant Psychiatrist.
Frequently asked questions
What is akathisia?
Akathisia is a feeling of inner restlessness or a strong urge to move, which is a recognised side effect of aripiprazole and some other antipsychotics; report this to your psychiatrist if it occurs, as adjustments can help.
Does Aripiprazole cause significant weight gain?
It is generally considered more weight-neutral than many other antipsychotics, though individual response varies and monitoring is still recommended.